Introduction
Due to unhealthy dietary habits and devoid of Dinacharya and Ritucharya, People have to face many skin diseases, life style diseases and autoimmune diseases. Psoriasis is one of them which is common dermatologic disease, affecting approximately 1.5 to 3% of Caucasians but less common in Asian.[1] Both males and females suffering equally.[2] Psoriasis is a non- infectious, chronic inflammatory disease of skin. It is characterized by well-defined erythematous plaques with silvery white scale appearance.[3]
All types of skin diseases are included under the heading of Kushtha. Charakacharya included in one of the Ashtamahagad.[4] AcharyaCharak described KushthaRogadhikar in which he classified Kushtha in to two major types; Maha-Kushtha and KshudraKushtha.[5] Amongst various types of Kustha, Eka-Kustha is one of them which having a symptoms like Asvedanam (Absence of perspiration), Mahavadstu, Matsyashakalopam (Look like fish scale).[6] According to the Dosha-Dushya and VyadhiAvastha (Disease condition) and Bala (Strength),Shodhan and ShamanChikitsa is described for the Kushtha in Ayurvedic literature. Repeated Shodhan is required in Kushtha due to BahuDoshavastha, to eliminate the aggravated Doshas which helps to treat the root cause of disease.But due to covid pandemic, ShamanaChikitsa was preferably given for 30 days.
Psoriasisis abnormal differentiation and keratinocyte hyperproliferation due to excessive multiplication of cells in the basal layers. The transit time of keratinocyte is shortened from approximately 28 to 5 days so that immature cells reach the stratum corneum prematurely.[7] Even though the etiology is unknown, the factors involved are genetic, biochemical, immune-pathological and environmental.[8] Precipitating factors like trauma, infections, sunlight, some drugs and emotions may flare up the disease.[1] As there is no available cure for the disease it has remained a great problem for the patients.[9] Patients not only suffer from physical problems, but also mental distress and social stigma.
Diagnosis of the Psoriasis is made mainly on the basis of clinical features that is [10]
- Erythematous plaques, covered with silvery white scales appearance.
- Extensor surface primarily involved.
- Koebner’s phenomenon present in the active phase of the disease.
- Worn off’s ring often present in the healing phase of the disease.
- Auspitz and candle grease signs are another classical feature of the disease.
The main goal of management is to alleviate symptoms and prevent relapse. In modern medicine, systemic treatment commonly used is photo chemotherapy with PUVA, retinoids, methotrexate and cyclosporine-A and corticosteroids. Locally coal tar preparations, calcipotriol, retinoid, corticosteroids and ultraviolet radiations are used to manage Psoriasis. [11] These medicines usually provide good symptomatic benefits, but in long term use causes number of side effects.
There are different types of Psoriasis which can be corelated to certain types of Kustha described in Samhitas. The description of Kushtha is present since Vedic period, Ekakushtha is described in GarudaPurana[12]and almost all Ayurvedic classics after that period i.e., Brihattrayi, Laghutrayiand all texts afterwards. Ekakushtha is mentioned in all Ayurvedic classics under KshudraKushtha and has predominance of Kapha and VataDosha.[13]AharajHetu like ViruddhaAahara, excessive consumption of Drava, Snigdha, Guru Aahar, Navannapan aand Viharaj Hetu like VegaDharana specially of urge of vomiting are major aetiologies. Sinful act and ill Manovritti(negative mentality) are associated mental factor for causing the Kushtha. [14]
Charaka has depicted classical features of Ekakushtha as Aswedanam, Mahavastu, and Matsyashakalopamam [15]and Sushruta described its symptoms as Krishna- ArunaVarnata.[16]Hetusevan leads to vitiation of Tridosha especially Vata and Kapha. These Dosha through TiryakvahiniSiras proceed to BahyaRogamarga i.e., Twacha, Rakta, Mamsa, and Lasika and leads to variety of Kustha..[17] Repeated Shodhana along with Shamana is main line of treatment.[18] Both AntahParimarjan and Bahiparimarjan therapies has been indicated in KushthaRoga. The present Allopathic treatment part is not sufficient to deal with the psoriasis. So, the Ayurveda has potential to deal with such kind of diseases.
Aim and Objective - To evaluate the role of Shamana Chikitsa in the management of Psoriasis.
Place of study - The present case study was done in the Department of Kayachikitsa, Shree Ayurved College and Pakwasa Hopsital, Nagpur
CASE REPORT:
Basic information of the patient
Age -66 years male Religion–Hindu
Socioeconomic status- Lower Middleclass
He was Security Guard and has mixed diet pattern. Patient has habit of chewing
Gutkha(1 packet daily) since last 40 years
PradhanVedana(Chief complaints)
Erythematous rashes on both hands, and both legs in the last 1 years.
Itching in rashes, with scaling on scratching.
Sometimes burning sensation
Vartaman Vyadhivritta(History of present illness)
The patient was asymptomatic before 1 year. After that he has developed complaint of scaly rashes on his both palm and on both legs which gradually progressed. There is severe itching in the rashes along with burning sensation, and scaling after scratching. On enquiry he said that lesions and symptoms was get aggravated on stress and having no relation to seasonal variation and remained constant for whole year. He took modern medication for about 6 months which provided symptomatic relief till treatment continues; on discontinuity of the treatment again the symptoms were exaggerated.
Purva Vyadhivritta(History of past illness)
Known case of hypertension since last 1 years on regular medication- Amlodipine 5mg once a day. Patient has no past history of any other chronic illness, burn, trauma.
KulajaVritta(Family history)
Not specific.
Vaiyaktikavritta(Personal history)
Appetite wasreduced. Predominant Rasa in Aharawas Madhura and Lavna Rasa. Sleep not regular due night shift, Habit of Divaswap, habit of constipation.
OnExamination
General condition was fair andafebrile.
Vitals werenormal.
Cardiovascular system, respiratory system and per abdomen examinations had
shown no deformity.
Prakriti(constitution) wasKapha-Pittaja.
Ashtavidha Pariksha
Nadi(pulse) was Kaphadhika-Tridoshaja.
Frequency and colour of Mutra (urine) were normal with no Daha.
Mala (stool) was constipated and feeling of incomplete evacuation of bowel.
Jihvawas Sama(coated), suggesting improper digestion.
Shabda(Speech) was clear and fluent.
Sparsha(touch) was Ruksha.
Drik(eyes) were normal.
Aakriti(appearance) was average built
Local Examination- Lesions were scaly erythematous plaque, present on both upper and lower limb. Lesions were symmetrical and well defined.
Auspitz sign – present koebner phenomenon– Present
Diagnosis- On the basis of clinical history and examination the condition was diagnosed
as Plaque Psoriasis.
Treatment protocol-
Total duration-30 days
Table no 1 - Showing Treatment Protocol
|
Medicine
|
Dose
|
Anupana
|
Route of
Administration
|
|
Raktashodhak Kwatha
|
40ml BD
|
Luke warm water
|
Oral
|
|
Haritaki Churna
|
10 gm BD
|
Luke warm water
|
Oral
|
|
Arogyavardhini Vati
|
500 mg BD
|
Luke warm water
|
Oral
|
|
Gandhak Rasayana
|
500 mg BD
|
Luke warm water
|
Oral
|
|
Sariva,
+Manjistha, each 2gm
+Lodhra, (prepare Kwath)
+Vidanga,
+Pippali
|
40ml BD
|
Luke warm water
|
Oral
|
|
777 oil
|
----
|
----
|
Local Application
|
PASI Score [19] - The current gold standard for assessment of extensive Psoriasis has been the Psoriasis area severity index (PASI). PASI combines the assessment of the severity of lesions and the area affected into a single score in the range 0 (no disease) to 72 (maximal disease). The PASI is a measure of the average redness, thickness and scaling of the lesions (each graded on a 0-4 scale), weighted by the area of involvement.
Steps in generating PASI score
- Divide body into four areas: head, arms, trunk to groin and legs to top of buttocks.
Generate a percentage for skin covered with psoriatic plaques for each area and convert that to 0-6 scale as bellow.
Table no 2 showing Rating Scale for Percentage of Area Involved.
|
Percentage
|
Rating scale
|
|
00
|
00
|
|
00 - < 10 %
|
01
|
|
10 - < 30 %
|
02
|
|
30 - < 50%
|
03
|
|
50 - <70%
|
04
|
|
70 - <90%
|
05
|
|
– 100%
|
06
|
- Generate an average score for the erythema, thickness and scale for each of the areas.
- Sum the score of erythema, thickness and scale for each of the areas.
- Multiply item (c) and (d) for each area and multiply that by 0.1, 0.2, 0.3 and 0.4 for head, arms, trunk and legs respectively.
- Add these scores to get the PASI score.
Assessment criteria:
The improvement of condition of the patient was assessed on the basis of PASI scale
Table no 3- PASI Score (Before treatment)
|
|
Head and neck
|
Arms
|
Trunk
|
Legs
|
Total
|
|
Skin area involved score
|
0.1
|
0.2
|
0.3
|
0.4
|
|
|
Redness
|
0
|
2
|
0
|
2
|
|
Thickening
|
0
|
3
|
0
|
4
|
|
Scaling
|
0
|
3
|
0
|
4
|
|
Total
|
0
|
1.6
|
0
|
4
|
5.6
|
Table no 4-PASI Score (After Treatment)
|
|
Head and neck
|
Arms
|
Trunk
|
Legs
|
Total
|
|
Skin area involved score
|
0.1
|
0.2
|
0.3
|
0.4
|
|
|
Redness
|
0
|
0
|
0
|
0
|
|
Thickening
|
0
|
0
|
0
|
1
|
|
Scaling
|
0
|
1
|
0
|
0
|
|
Total
|
0
|
0.2
|
0
|
0.4
|
0.6
|
Observation:
Picture no. 1: Showing before treatment and after treatment.

RESULT:
Here, significant improvements in the subjective parameters of the patient were seen. Also, the considerable reduction in the PASI score from 5.6 to 0.6 was observed.
References
[1] SH Ibbotson: “Davidson’s principles and practice of Medicine”: 23rd edition: Elsevier publication: Chapter 29 – Dermatology P g -1248
[2] SH Ibbotson: “Davidson’s principles and practice of Medicine”: 23rd edition: Elsevier publication: Chapter 29 – Dermatology P g -1248
[3] Z. Zaidi and S.W. Lanigan: “Dermatology in Clinical practice”: 2010 Springer- Verlag London Limited, Immune system of the skin, p g 185.
[4] Shukla and RaviDutt Tripathi, Agnivesh, Charak samhita, Chakrapani Commentary, IndriyasthanChapter 9, shloka 8, Varanasi:Chowkhamba Sanskrit Pratishthan 2009.
[5] Shukla and Ravi Dutt Tripathi, Agnivesh, Charak samhita, Chakrapani Commentary, NidansthanChapter 5, shloka 4, Varanasi:Chowkhamba Sanskrit Pratishthan 2009. \
[6] Tripathi Bramhananda, Charak Samhita, Chapter 7/21, Chaukhamba Surbharati Publication, Varanasi, 2009
[7] SH Ibbotson: “Davidson’s principles and practice of Medicine”: 23rd edition: Elsevier publication: Chapter 29 – Dermatology P g -1248
[8] Michael Hertl: “Autoimmune diseases of skin”: third edition: Springer Wein New York: p g no. 328-331.
[9] Khanna N: “Illustrated synopsis of Dermatology and Sexually transmitted diseases”: Edition 2005: Jaypee publishers and distributors; P g no. 38.
[10] De Korte J, Sprangers MAG, Mombers FMC et al: “Quality of life in patients of Psoriasis: A systemic literature review”: J invest Dermatol symp Proc 2004: 9: 140-7.
[11] Fitzpatrick’s: Dermatology in General Medicine: vol- 1; 7th edition; Mc Graw hill Companies: P g 185.
[12] Bhattacharya R S: Garuda Purana: Maharshi Vedvays: Varanasi: Edition 1964, Chaukhambha Sanskrit Series; P g no. 38.
[13] Tripathi R, Shukla V. Charak Samhita. Volume 2; Chikitsasthana, 7th chapter-, verse no. 29-30: Varanasi; Chaukhamba Sanskrit Pratisthan;2017; p g no. 185
[14] Tripathi R, Shukla V. Charak Samhita. Volume 2; Chikitsasthana, 7th chapter-, verse no.4-8; Varanasi; Chaukhamba Sanskrit Pratisthana; 2017; page no 181
[15] Tripathi R, Shukla V. Charak Samhita. Volume 2; Chikitsasthana, 7th chapter-, verse no. 21-41; Varanasi; Chaukhamba Sanskrit Pratisthana; 2017; p g no. 184, 186
[16] Atahvale P. G. Sushruta Samhita. Nidansthana. 5th chapter-Verse no 10; Nagpur; Godavari Book Publishers and book promoters; 2008 pg no. 472
[17] Tripathi B. Astanga Hruday Samhita; Nidansthana,14th chapter-, verse no. 3a; Delhi; Chaukhamba Sanskrit Pratisthana; 2015 p g no. 527
[18] Tripathi R, Shukla V. Charak Samhita. Volume 2; Chikitsasthana, 7th chapter-, verse no. 29-30; Varanasi; Chaukhamba Sanskrit Pratisthana; 2017; p g no 185
[19] W Sterry, R Paus, W Burgdorf: “Sterry Dermatology”: Edition 2006; Thieme; New York; P g 267.
[20] Tripathi B. Astanga Hruday Samhita; Nidansthana,14th chapter-, verse no. 3; Delhi; Chaukhamba Sanskrit Pratisthana; 2015; p g no. 527
Source of Support : None declared
Conflict of interest : Nil