About Author
Wasnik D1,Mahto R2,Dachewar D3,
1 Assistant Professor, Department of Kayachikitsa, , Shri Ayurved Mahavidyalaya, Nagpur, Maharashtra
2 Associate Professor Kayachikitsa Department , AIIA new Delhi
3 HOD & Professor, Department of Kayachikitsa, Shri Ayurved Mahavidyalaya, Nagpur
Correspondence Address
Dr Kundan Wasnik
BAMS MD (Kayachikitsa)
Assistant Professor, Shri Ayurved Mahavidyalaya Nagpur
Contact No. : 9175073644, Email : kuindanwasnik@gmail.com
Date of Acceptance : 29 Sep 2026
Date of Publication : 30 Sep 2026
Article ID : SD-IJAY_196
How to cite this article : http://doi.org/10.55552/SDNJAY.2026.4302
Abstract
Diabetes mellitus is a rapidly escalating global health concern, primarily attributed to sedentary lifestyle, psychological stress, and unhealthy dietary habits. Despite the availability of a wide range of pharmacological interventions in contemporary medicine, their long-term use is frequently associated with adverse effects and suboptimal patient satisfaction. According to the World Health Organization, the global prevalence of diabetes has increased markedly from 108 million in 1980 to 422 million in 2014, underscoring the need for more comprehensive and sustainable management approaches.
Modern medical strategies largely focus on achieving target-oriented glycemic control; however, recent evidence emphasizes the importance of a multidimensional approach for improved long-term outcomes. In Ayurveda, diabetes is correlated with Prameha, a group of metabolic disorders classified under Anushangi Vyadhi (chronic and relapsing conditions). Ayurvedic management adopts a holistic and individualized approach, considering etiological factors (Nidana), clinical features (Lakshana), pathogenesis (Samprapti), systemic involvement, and the strength of both the patient (Rogi Bala) and disease (Vyadhi Bala).
Classical Ayurvedic literature describes numerous formulations for the management of Prameha. Among these, Mamajjaka Ghana Vati has gained considerable attention due to its diverse pharmacological properties, including antioxidant, antihyperlipidemic, nephroprotective, and ulcer-healing activities. These properties may contribute not only to glycemic control but also to the prevention and management of diabetic complications.
Considering the challenges in selecting appropriate therapeutic interventions for newly diagnosed diabetic patients, the present review aims to critically evaluate Mamajjaka Ghana Vati with respect to its pharmacological profile, mechanism of action, and clinical efficacy based on available scientific evidence.
Key words – Diabetes, Prameha, Mamajjaka Ghana Vati, Anti-oxidant, Anti-hyperlipidemia, nephroprotective