ISSN : 2584-0304

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Year - 2026Volume - 4Issue - 1Pages - 69-75

ANTI-INFLAMMATORY ACTIVITY OF GANDHAMADANA AGADA: A COMPREHENSIVE REVIEW

 24 Mar 2026  6

About Author

Thakare D1,Nandedkar D2,
1 PG Scholar , Yerala ayurvedic medical College Kharghar Navi Mumbai
2 HOD Agadtantra avum Vidhi Vaidyaka , Yerala ayurvedic medical College Kharghar Navi Mumbai

Correspondence Address

V.H.B. Colony Achalpur
Contact No. : 8412068113, Email : iamprajwalthakare@gmail.com

Date of Acceptance : 31 Mar 2026

Date of Publication : 31 Mar 2026

Article ID : SD-IJAY_169

How to cite this article : http://doi.org/10.55552/SDNJAY.2026.4110

Abstract

Gandhamadana Agada is a classical polyherbal formulation described in the Ashtanga Hridaya for the management of Keeta Visha (insect bites) and Loota Visha (spider bites). These conditions are characterized by acute inflammatory responses, including shotha (swelling), vedana (pain), and localized burning sensations. This review aims to analyze the anti-inflammatory potential  of            Gandhamadana Agada by evaluating its eight herbal constituents: Tagara, Lodhra, Vaca, Katvi, Patha, Ela, Tamal Patra, and Kunkuma. By bridging traditional Ayurvedic principles with modern pharmacological markers such as COX-II and TNF-alpha, the study highlights the multi-targeted mechanism of the formulation. The review concludes that Gandhamadana Agada serves as a potent, cost-effective, and safe alternative to synthetic drugs for treating toxicological and traumatic edema.

Keywords: Gandhamadana Agada, Agada Tantra, Shothahara, Inflammation, COX-II, Ayurveda 

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