CALL FOR PAPERS Upcoming issue - Jun-2026 Last date of submission 25th of Jun. 2026
ISSN : 2584-0304
CALL FOR PAPERS Upcoming issue - Jun-2026 Last date of submission : 25th of Jun. 2026
Correspondence Address
V.H.B. Colony Achalpur Contact No. : 8412068113, Email : iamprajwalthakare@gmail.com
Date of Acceptance : 31 Mar 2026
Date of Publication : 31 Mar 2026
Article ID : SD-IJAY_169
How to cite this article : http://doi.org/10.55552/SDNJAY.2026.4110
Gandhamadana Agada is a classical polyherbal formulation described in the Ashtanga Hridaya for the management of Keeta Visha (insect bites) and Loota Visha (spider bites). These conditions are characterized by acute inflammatory responses, including shotha (swelling), vedana (pain), and localized burning sensations. This review aims to analyze the anti-inflammatory potential of Gandhamadana Agada by evaluating its eight herbal constituents: Tagara, Lodhra, Vaca, Katvi, Patha, Ela, Tamal Patra, and Kunkuma. By bridging traditional Ayurvedic principles with modern pharmacological markers such as COX-II and TNF-alpha, the study highlights the multi-targeted mechanism of the formulation. The review concludes that Gandhamadana Agada serves as a potent, cost-effective, and safe alternative to synthetic drugs for treating toxicological and traumatic edema.
Keywords: Gandhamadana Agada, Agada Tantra, Shothahara, Inflammation, COX-II, Ayurveda
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